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Home / All Peptides / General Health/Wellness / Melanotan 1
General Health/Wellness

Melanotan 1

CAS # 75921-69-6
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Compound Overview

Understanding the Melanotan 1 Research Peptide

Melanotan 1 (afamelanotide class) is a linear alpha-MSH analog research peptide studied for selective MC1R activation and melanogenesis signaling in cell-based and preclinical models.

Melanotan 1 is a linear analog of alpha-melanocyte-stimulating hormone with a substitution that extends its stability. It shows strong selectivity for the melanocortin-1 receptor (MC1R), the receptor governing melanin synthesis, and is used in laboratories studying pigmentation biology, UV response pathways, and MC1R pharmacology.

Research Applications

  • MC1R receptor selectivity and activation studies
  • Melanogenesis and pigmentation biology research
  • UV response and photoprotection models
  • Comparative studies against cyclic melanocortin analogs

Handling & Storage

Supplied as a lyophilized powder. Store sealed vials in a cool, dry place away from light; refrigerate after reconstitution with bacteriostatic water and avoid repeated freeze-thaw cycles.

This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

Chemical Reference

Melanotan 1 Structure

Melanotan 1 molecular structure
CAS #75921-69-6
Molecular FormulaC78H111N21O19
Molecular Weight~1,646.8 g/mol
PubChem ID16197727
Documentation over decoration

Proof belongs on the product page.

Every batch of Melanotan 1 is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
Melanotan 1 · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

References

A curated list of published, peer-reviewed papers indexed in PubMed where Melanotan 1 has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Wensink D et al. (2021) · Expert Rev Clin Pharmacol
Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria
PubMed · 33507118 ↗
02
Wu J et al. (2021) · J Drugs Dermatol
Afamelanotide: An Orphan Drug with Potential for Broad Dermatologic Applications
PubMed · 33683075 ↗
03
Polańska A et al. (2024) · Postepy Dermatol Alergol
Afamelanotide in protoporphyria and other skin diseases: a review
PubMed · 38784937 ↗
Common Questions

Frequently Asked Questions

What is Melanotan 1 used for in research?

Melanotan 1 (afamelanotide class) is a linear alpha-MSH analog research peptide studied for selective MC1R activation and melanogenesis signaling in cell-based and preclinical models. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.

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