5-Amino-1MQ is a small molecule that inhibits the enzyme Nicotinamide N-methyltransferase (NNMT), which prevents the enzyme NAMPT from converting NAM into NMN, a critical precursor to NAD+; lowering levels of cellular NAD+. By inhibiting this conversion process, 5-Amino-1MQ has shown to increase cellular NAD+ levels.
5-Amino-1MQ – Research Compound
5-Amino-1MQ is a small molecule that blocks the enzyme Nicotinamide N-methyltransferase (NNMT). This enzyme changes the NAD+ salvage pathway by adding a methyl group to nicotinamide, a form of vitamin B3. When NNMT interferes, the enzyme NAMPT cannot turn nicotinamide into NMN, which is needed to create NAD+. Because NAD+ drives cell energy, this shift directly affects how the body uses fuel.
Researchers study this compound to better understand metabolism. Studies show it can raise energy use and increase fat breakdown in animals. Scientists also examine how it affects fat cell growth, lipolysis, and age-related changes tied to. By blocking this pathway, it raises NAD+ levels, supports enzymes like sirtuins, and changes how cells manage energy.
Scientists store 5-Amino-1MQ in a cool, dry place away from light. They follow lab safety rules whenever they handle it. It is not a food, drug, or cosmetic, and no person or animal should consume it.
This compound comes in powder form with purity above 98.5%. Researchers use it only for lab work, including in-vitro and early-stage studies. With it, they gain a reliable tool to explore metabolism, NNMT activity, and energy balance.
Key Benefits of 5-Amino-1MQ
Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.
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