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Home / All Peptides / Growth Hormone Secretagogue / IGF-1 LR3
Growth Hormone Secretagogue

IGF-1 LR3

CAS # 946870-92-4
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Compound Overview

About IGF-1 LR3

IGF-1 LR3 is a long-acting analog of insulin-like growth factor 1 with an arginine substitution and 13 amino acid extension, studied in cell growth, proliferation, and metabolic signaling research.

IGF-1 LR3 is a modified research analog of insulin-like growth factor 1 featuring an arginine substitution at position 3 and an N-terminal 13 amino acid extension. These changes sharply reduce binding to IGF-binding proteins, extending its active life and making it a common tool in cell culture work examining proliferation, differentiation, and IGF-1 receptor signaling.

Research Applications

  • Cell proliferation and differentiation studies in vitro
  • IGF-1 receptor signaling and binding protein research
  • Muscle and tissue cell culture models
  • Growth factor stability and analog comparison studies

Handling & Storage

Supplied as a lyophilized powder. Store sealed vials in a cool, dry place away from light; refrigerate after reconstitution with bacteriostatic water and avoid repeated freeze-thaw cycles.

This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

Documentation over decoration

Proof belongs on the product page.

Every batch of IGF-1 LR3 is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
IGF-1 LR3 · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

Understanding the Science of IGF-1 LR3

A curated list of published, peer-reviewed papers indexed in PubMed where IGF-1 LR3 has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Lu Z et al. (2023) · Appl Microbiol Biotechnol
Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris
PubMed · 37261455 ↗
02
White A et al. (2023) · J Dev Orig Health Dis
Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets
PubMed · 37114757 ↗
03
Stremming J et al. (2022) · Front Physiol
Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep
PubMed · 36091374 ↗
Common Questions

Frequently Asked Questions

What is IGF-1 LR3 used for in research?

IGF-1 LR3 is a long-acting analog of insulin-like growth factor 1 with an arginine substitution and 13 amino acid extension, studied in cell growth, proliferation, and metabolic signaling research. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.

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