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Home / All Peptides / Hormonal / Kisspeptin
Hormonal

Kisspeptin

CAS # 374675-21-5
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Compound Overview

About Kisspeptin

Kisspeptin is the master upstream regulator of the reproductive hormone axis, studied for GnRH neuron activation and KISS1R signaling in endocrine research models.

Kisspeptin is a research peptide encoded by the KISS1 gene that acts as the principal upstream trigger of the hypothalamic-pituitary-gonadal axis. By activating KISS1R on GnRH neurons it initiates the hormonal cascade governing reproductive endocrinology, making it a central tool in preclinical studies of puberty signaling, fertility biology, and hormone pulsatility.

Research Applications

  • GnRH neuron activation and KISS1R signaling studies
  • Hypothalamic-pituitary-gonadal axis research
  • LH and FSH pulsatility models
  • Reproductive endocrinology preclinical studies

Handling & Storage

Supplied as a lyophilized powder. Store sealed vials in a cool, dry place away from light; refrigerate after reconstitution with bacteriostatic water and avoid repeated freeze-thaw cycles.

This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

Chemical Reference

Kisspeptin Structure

Kisspeptin molecular structure
CAS #374675-21-5
Molecular FormulaC63H83N17O14
Molecular Weight~1,302.4 g/mol
PubChem ID25240297
Documentation over decoration

Proof belongs on the product page.

Every batch of Kisspeptin is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
Kisspeptin · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

References

A curated list of published, peer-reviewed papers indexed in PubMed where Kisspeptin has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Li Z et al. (2024) · Nat Commun
Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src
PubMed · 38346942 ↗
02
Navarro VM (2020) · Nat Rev Endocrinol
Metabolic regulation of kisspeptin - the link between energy balance and reproduction
PubMed · 32427949 ↗
03
Abreu AP et al. (2016) · Lancet Diabetes Endocrinol
Pubertal development and regulation
PubMed · 26852256 ↗
04
Radwańska P et al. (2023) · Sci Rep
Kisspeptin-10 increases collagen content in the myocardium by focal adhesion kinase activity
PubMed · 37968564 ↗
Common Questions

Frequently Asked Questions

What is Kisspeptin used for in research?

Kisspeptin is the master upstream regulator of the reproductive hormone axis, studied for GnRH neuron activation and KISS1R signaling in endocrine research models. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.

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