🔥 40% OFF SITEWIDE — Discount Already Applied Free Shipping on Orders Over $200 Third-Party Tested · 99%+ Purity Guaranteed Shop the Sale → 🔥 40% OFF SITEWIDE — Discount Already Applied Free Shipping on Orders Over $200 Third-Party Tested · 99%+ Purity Guaranteed Shop the Sale → 🔥 40% OFF SITEWIDE — Discount Already Applied Free Shipping on Orders Over $200 Third-Party Tested · 99%+ Purity Guaranteed Shop the Sale → 🔥 40% OFF SITEWIDE — Discount Already Applied Free Shipping on Orders Over $200 Third-Party Tested · 99%+ Purity Guaranteed Shop the Sale →
Home / All Peptides / Cognitive Enhancement / Semax
Cognitive Enhancement

Semax

CAS # 80714-61-0
SELECT SIZE / AMOUNT
Bundle & Save up to 10% off
Total
$50.00$83.00
SAVE 40%

✦ Orders placed before 4PM PT ship the same business day

Compound Overview

Understanding Semax: Research Applications and Mechanisms

Semax is a synthetic ACTH(4-10) analog research peptide developed in Russian neuroscience programs, studied for BDNF expression, neuroprotection, and cognitive-related signaling in preclinical models.

Semax is a heptapeptide research compound derived from the ACTH(4-10) fragment with a C-terminal Pro-Gly-Pro extension for stability. Originating from Russian neuropharmacology research, it is studied for its influence on brain-derived neurotrophic factor (BDNF) expression, melanocortin receptor signaling, and neuroprotective endpoints in preclinical models.

Research Applications

  • BDNF and neurotrophin expression studies
  • Neuroprotection models in preclinical research
  • Melanocortin receptor signaling in the CNS
  • Cognitive and attention-related preclinical models

Handling & Storage

Supplied as a lyophilized powder. Store sealed vials in a cool, dry place away from light; refrigerate after reconstitution with bacteriostatic water and avoid repeated freeze-thaw cycles.

This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

Chemical Reference

Semax Structure

Semax molecular structure
CAS #80714-61-0
Molecular FormulaC37H51N9O10S
Molecular Weight~813.9 g/mol
PubChem ID9811102
Documentation over decoration

Proof belongs on the product page.

Every batch of Semax is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
Semax · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

References

A curated list of published, peer-reviewed papers indexed in PubMed where Semax has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Liu R et al. (2025) · Br J Pharmacol
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice
PubMed · 40692165 ↗
02
Rahman OF et al. (2026) · J Am Acad Orthop Surg Glob Res Rev
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
PubMed · 41490200 ↗
03
Panikratova YR et al. (2020) · Dokl Biol Sci
Functional Connectomic Approach to Studying Selank and Semax Effects
PubMed · 32342318 ↗
04
Radchenko AI et al. (2025) · Acta Naturae
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease
PubMed · 41479572 ↗
Common Questions

Frequently Asked Questions

What is Semax used for in research?

Semax is a synthetic ACTH(4-10) analog research peptide developed in Russian neuroscience programs, studied for BDNF expression, neuroprotection, and cognitive-related signaling in preclinical models. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.

Stay Ahead of the Research

Get updates on new peptides, purity reports, and research insights.