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Semax

CAS # 80714-61-0
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Research Peptide

About Semax

Semax is a synthetic ACTH(4-10) analog research peptide developed in Russian neuroscience programs, studied for BDNF expression, neuroprotection, and cognitive-related signaling in preclinical models.

This compound is supplied for research use only. Not for human consumption.

Key Information

Molecular Details

CAS #80714-61-0
Molecular FormulaC37H51N9O10S
Molecular Weight813.9 g/mol

Research Applications

  • BDNF and neurotrophin expression studies
  • Neuroprotection models in preclinical research
  • Melanocortin receptor signaling in the CNS
  • Cognitive and attention-related preclinical models

For research use only. This compound is not intended for diagnostic or therapeutic use.

Chemical Reference

Understanding Semax: Research Applications and Mechanisms

Semax molecular structure
CAS #80714-61-0
Molecular FormulaC37H51N9O10S
Molecular Weight~813.9 g/mol
PubChem ID9811102
Certificate of Analysis

Proof of Purity

Every batch of Semax is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
Semax · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

References

A curated list of published, peer-reviewed papers indexed in PubMed where Semax has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Liu R et al. (2025) · Br J Pharmacol
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice
PubMed · 40692165 ↗
02
Rahman OF et al. (2026) · J Am Acad Orthop Surg Glob Res Rev
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
PubMed · 41490200 ↗
03
Panikratova YR et al. (2020) · Dokl Biol Sci
Functional Connectomic Approach to Studying Selank and Semax Effects
PubMed · 32342318 ↗
04
Radchenko AI et al. (2025) · Acta Naturae
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease
PubMed · 41479572 ↗
Common Questions

Frequently Asked Questions

What is Semax used for in research?

Semax is a synthetic ACTH(4-10) analog research peptide developed in Russian neuroscience programs, studied for BDNF expression, neuroprotection, and cognitive-related signaling in preclinical models. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.