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Home / All Peptides / Growth Hormone Secretagogue / Sermorelin
Growth Hormone Secretagogue

Sermorelin

CAS # 86168-78-7
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Compound Overview

About Sermorelin

Sermorelin is a GHRH fragment research peptide comprising the first 29 amino acids of native growth hormone-releasing hormone, widely used as a reference compound in pituitary and GH axis studies.

Sermorelin is a synthetic peptide corresponding to the 1-29 fragment of growth hormone-releasing hormone — the shortest sequence retaining full biological activity at the GHRH receptor. Its close mimicry of native GHRH pulsatility makes it a foundational reference compound for laboratories studying pituitary somatotroph response and physiologic growth hormone release patterns.

Research Applications

  • GHRH receptor fragment activity studies
  • Physiologic growth hormone pulsatility research
  • Pituitary somatotroph signaling models
  • Structure-activity relationship studies of GHRH fragments

Handling & Storage

Supplied as a lyophilized powder. Store sealed vials in a cool, dry place away from light; refrigerate after reconstitution with bacteriostatic water and avoid repeated freeze-thaw cycles.

This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

Chemical Reference

Sermorelin Structure

Sermorelin molecular structure
CAS #86168-78-7
Molecular FormulaC149H246N44O42S
Molecular Weight~3,357.9 g/mol
PubChem ID16132413
Documentation over decoration

Proof belongs on the product page.

Every batch of Sermorelin is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
Sermorelin · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

References

A curated list of published, peer-reviewed papers indexed in PubMed where Sermorelin has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Mendias CL et al. (2026) · Sports Med
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance
PubMed · 41966639 ↗
02
Rahman OF et al. (2026) · J Am Acad Orthop Surg Glob Res Rev
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
PubMed · 41490200 ↗
03
Memdouh S et al. (2021) · Drug Test Anal
Advances in the detection of growth hormone releasing hormone synthetic analogs
PubMed · 34665524 ↗
04
Walker RF (2006) · Clin Interv Aging
Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?
PubMed · 18046908 ↗
Common Questions

Frequently Asked Questions

What is Sermorelin used for in research?

Sermorelin is a GHRH fragment research peptide comprising the first 29 amino acids of native growth hormone-releasing hormone, widely used as a reference compound in pituitary and GH axis studies. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.

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