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Home / All Peptides / Cognitive Enhancement / Dihexa
Cognitive Enhancement

Dihexa

CAS # 1401708-83-5
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Compound Overview

About Dihexa

Dihexa is a small-molecule angiotensin IV derivative studied for hepatocyte growth factor potentiation and synaptogenesis in preclinical cognitive research models.

Dihexa is an orally stable angiotensin IV-derived research compound developed at Washington State University. It is studied for its capacity to potentiate hepatocyte growth factor (HGF) and its receptor c-Met, a pathway linked to synapse formation, with preclinical work examining synaptogenesis and cognition-related endpoints in animal models.

Research Applications

  • HGF and c-Met pathway potentiation studies
  • Synaptogenesis and dendritic spine research
  • Preclinical cognition and memory models
  • Blood-brain barrier penetration studies

Handling & Storage

Supplied as a lyophilized powder. Store sealed vials in a cool, dry place away from light; refrigerate after reconstitution and avoid repeated freeze-thaw cycles.

This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

Chemical Reference

Dihexa Structure

Dihexa molecular structure
CAS #1401708-83-5
Molecular FormulaC27H44N4O5
Molecular Weight~504.7 g/mol
PubChem ID129010512
Documentation over decoration

Proof belongs on the product page.

Every batch of Dihexa is independently tested for identity and purity, and ships with its own Certificate of Analysis — lot information included, where a researcher can actually find it.

View Testing Documentation →
PRISTINEAMINOS Certificate of Analysis
Dihexa · Current batch
IdentityConfirmed
Purity≥99%
OriginUnited States

Batch COA provided with every order.

Selected Studies · Peer-Reviewed Literature

References

A curated list of published, peer-reviewed papers indexed in PubMed where Dihexa has been studied. Provided for research context only — linking to the literature does not constitute endorsement of any therapeutic application.

01
Rahman OF et al. (2026) · J Am Acad Orthop Surg Glob Res Rev
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
PubMed · 41490200 ↗
02
Benoist CC et al. (2014) · J Pharmacol Exp Ther
The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system
PubMed · 25187433 ↗
03
McCoy AT et al. (2013) · J Pharmacol Exp Ther
Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents
PubMed · 23055539 ↗
Common Questions

Frequently Asked Questions

What is Dihexa used for in research?

Dihexa is a small-molecule angiotensin IV derivative studied for hepatocyte growth factor potentiation and synaptogenesis in preclinical cognitive research models. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.

How is purity verified?

Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.

When does my order ship?

Orders placed before 4PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.

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